The German Center for Neurodegenerative Diseases (DZNE) is a world-leading internationally oriented research center, committed to discovering new approaches to prevent and treat neurodegenerative diseases. To this end, researchers at ten DZNE sites across Germany pursue a translational and interdisciplinary strategy comprising five interconnected areas: fundamental research, clinical research, health care research, population health science, and systems medicine. www.dzne.de

Postdoctoral Researcher (f/m/d) in the Group “Mechanisms of Propagation”

Code: 6012/2020/10

The main task of the research group Mechanisms of Propagation is to elucidate underlying mechanisms in disease propagation and spreading in neurodegenerative diseases with a focus on Amyotrophic Lateral Sclerosis, Frontotemporal Dementia (FTD) and Parkinson’s disease (PD). Using innovative animal models and patient samples, we try to understand how and why protein aggregates are transmitted from cell to cell. We also explore transmission to non-neuronal cells and try to pinpoint the contribution of peripheral inflammation. Furthermore, epigenetic profiling of different cell populations allows us to discover new pathways involved in ALS, PD and FTD and to identify new therapeutic targets.

Your tasks

• Experimental work includes molecular cloning, culture of primary cells, working with transgenic animals, RNA Seq as well as biochemical methods
• Active participation in experimental work, experimental design, data generation, data analyses, and interpretation of results
• Prepare and write manuscripts for publication in international scientific journals
• Oral presentation of results on local, national, and international conferences

Requirements

• A keen interest in neurodegenerative diseases and a profound knowledge in neuroscience
• Experience in working with transgenic mouse models and analyzing transcriptomic data are advantageous
• Successful candidates have a PhD in molecular biology, neuroscience, biochemistry (or a PhD in a related field)
• English language is a prerequisite
• We are looking for candidates who are open-minded, creative team-player, enthusiastic, have strong analytical skills, think critically, and with good social skills

We offer

• Working in an international team within a stimulating research environment and with very well equipped laboratories
• An international environment characterized by a strong focus on science and research
• A high potential for the individual development of our employees
• 2 years with the possibility of prolongation
• Targeted personnel development
• Employment, payment and social benefits are determined by the Public Sector Collective Agreement (Tarifvertrag für den öffentlichen Dienst – TVöD Bund)

Application files: CV, Motivation letter, Bachelor and Master qualification, Reference letters, certificates

Site

Ulm

Contact details

Herr Daniel Preiß

Working hours

full-time

Contract length

2 years, extension possible

Payment, social benefits

according to TVöD Bund

Application deadline

31.12.2020